Fifty years after Tobe Hooper’s THE TEXAS CHAIN SAW MASSACRE shook the world and transformed global cinema and pop culture, CHAIN REACTIONS explores the film’s deep impact and lasting legacy on five remarkable artists – Patton Oswalt, Takashi Miike, Alexandra Heller-Nicholas, Stephen King, and Karyn Kusama. They share their early memories, sensory experiences, and childhood traumas related to the film. By blending fresh footage with unseen outtakes and examining personal reactions to various formats (16mm, 35mm, VHS, digital), CHAIN REACTIONS dives into how this gritty, low-budget indie flick embedded itself in our collective fears and changed the cultural landscape forever.